Why the study?
Does sympathetic reinnervation of the sinus node improve chronotropic response to exercise in cardiac transplant recipients?
Population
61 subjects including 13 recent cardiac transplant recipients, 28 late CT recipients, and 20 control subjects.
Comparison
Assessment of sinus node sympathetic… vs Control subjects and comparison between…
Design
Cross-sectional
Authors
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Reinnervation was associated with restored chronotropic response post-transplant; supports partial recovery but leaves open effects on exercise capacity.
Does sympathetic reinnervation of the sinus node improve chronotropic response to exercise in cardiac transplant recipients?
Sympathetic reinnervation of the sinus node after cardiac transplantation partially restores normal heart rate response to exercise, though it does not significantly improve maximal oxygen consumption or exercise duration.
Wilson et al. (2000) studied this question.
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