Why the study?
How does heart rate variability change over 5 years following orthotopic heart transplantation compared to healthy controls?
Population
40 subjects: 20 patients who underwent orthotopic heart transplantation, and 20 healthy subjects as a…
Comparison
Orthotopic heart transplantation vs Healthy subjects
Design
Cohort
Follow-up
5 years
Authors
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HRV recovery remains incomplete after transplantation; leaves open whether serial monitoring informs prognosis or management.
How does heart rate variability change over 5 years following orthotopic heart transplantation compared to healthy controls?
Heart rate variability progressively increases over the first 3 years following orthotopic heart transplantation, suggesting possible enhanced beta-adrenergic receptor sensitivity or limited sympathetic reinnervation.
Folino et al. (1993) studied this question.
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