Key result
Heart transplant recipients exhibited lower baseline respiratory sinus arrhythmia than controls (1.45 vs 5.80 ln ms2), which significantly increased during early graded exercise (P<0.01).
Why the study?
Does graded exercise affect respiratory sinus arrhythmia in heart transplanted subjects compared to healthy controls?
Population
41 subjects who had undergone heart transplantation 28 months earlier, and 6 age-matched control subjects.
Comparison
Graded exercise on a cycle ergometer vs Age-matched healthy control subjects
Design
Cross-sectional
Authors
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RSA in transplanted hearts during exercise may indicate reinnervation; leaves open its mechanisms, evolution, and clinical relevance.
Observational (n=47)
Does graded exercise affect respiratory sinus arrhythmia in heart transplanted subjects compared to healthy controls?
Absolute Event Rate: 1.45% vs 5.8%
Radaelli et al. (1996) conducted an observational in Heart transplantation (n=47). Heart transplantation vs. Age-matched controls was evaluated on Respiratory sinus arrhythmia at baseline (ln ms2). Heart transplant recipients exhibited lower baseline respiratory sinus arrhythmia than controls (1.45 vs 5.80 ln ms2), which significantly increased during early graded exercise (P<0.01).
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