Key result
Orthotopic heart transplantation was associated with an almost absent high-frequency component of the R-R interval compared to controls (2.9 vs. 104 ms2; P<0.001), with no significant difference in blood pressure variations.
Why the study?
Does respiratory-related blood pressure variability depend on respiratory heart rate variations in patients after heart transplantation?
Population
12 patients between 16 and 23 days after orthotopic heart transplantation and 12 age- and sex-matched normal…
Comparison
Power spectral analysis of R-R interval, blood… vs Age- and sex-matched normal control subjects
Design
Case-control
Follow-up
30 minutes
Authors
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Respiratory BP fluctuations may persist without HR variation post-transplant; leaves open non-autonomic mechanisms in observational data.
Case-Control (n=24)
Does respiratory-related blood pressure variability depend on respiratory heart rate variations in patients after heart transplantation?
Absolute Event Rate: 2.9% vs 104%
p-value: p=<0.001
Respiratory variations of blood pressure do not depend significantly on respiratory heart rate variations, as demonstrated in heart transplant recipients lacking heart rate variability.
Macor et al. (1994) conducted a case-control in Heart transplantation (n=24). Orthotopic heart transplantation vs. Age- and sex-matched normal control subjects was evaluated on High-frequency (HF) component of the power spectrum of the R-R interval (p=<0.001). Orthotopic heart transplantation was associated with an almost absent high-frequency component of the R-R interval compared to controls (2.9 vs. 104 ms2; P<0.001), with no significant difference in blood pressure variations.
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