Why the study?
Does maternal warfarin exposure during pregnancy affect the physical and mental development of children?
Does maternal warfarin exposure during pregnancy affect the physical and mental development of children?
Maternal warfarin use during pregnancy did not significantly affect the physical and mental development of the children in this small cohort.
Answers are grounded in this paper and cite their sources.
May support indicated warfarin use in pregnancy; leaves open need for larger prospective confirmation.
Twenty-two children whose mothers took the oral coumarin anticoagulant warfarin during pregnancy were seen, to assess their physical and mental development; a comparison was made with matched controls. No significant difference was observed between the study group and controls, nor within the study group according to the period of gestation when their mothers took warfarin.
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CHONG et al. (1984) studied this question.
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