Population
Detergent-skinned fiber bundles of Limulus telson muscle
Comparison
Calcium activation vs Unstimulated fibers
Design
Preclinical
Authors
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Does not yet alter clinical sarcomere models; leaves open whether calcium-induced filament shortening occurs in mammalian myocardium.
Calcium activation of Limulus telson muscle causes thick filament shortening via breakage within a defined distal region.
Levine et al. (1991) studied this question.
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