Why the study?
Adenoviruses rarely cause central nervous system involvement, with limited clinical reports of severe presentations.
Clinicians should be aware of possible central nervous system involvement in adenovirus infection, which can lead to fatal viral sepsis and encephalitis.
May indicate fatal CNS involvement in adenovirus type 7; case report leaves open incidence and causality.
Adenoviruses are highly prevalent pathogens responsible for a wide range of clinical diseases, including respiratory tract infection, acute gastroenteritis, and conjunctivitis. However, adenovirus infection is rarely associated with central nervous system involvement. Here, we report a fatal viral sepsis and encephalitis in a child caused by a human adenovirus type 7 infection. We detected human adenovirus type 7 in the patient's nasopharyngeal swab, blood, and cerebrospinal fluid. Our findings indicate clinicians should be aware of the possible central nervous system involvement in adenovirus infection.
No takes yet. Share an insight, caveat, or question.
Zhao et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: