October 4, 2022NeurogliaOpen Access

Overview of Neuroglia Activation, Chronic Neuroinflammation, Remodeling, and Impaired Cognition Due to Perivascular Adipose Tissue-Derived Extracellular Vesicle Exosomes in Obesity and Diabetes

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Population

Preclinical db/db mouse models and humans with T2DM

Design

Overview

Authors

MHMelvin R. HaydenUniversity of Missouri Hospital

Discussion

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Implication

Suggests new therapeutic avenues for cognitive impairment in obesity and diabetes; leaves open clinical translation pending prospective studies.

Structured PICO

Population

Preclinical obese, insulin and leptin resistant, diabetic db/db mouse models and humans with T2DM

This review highlights a potential mechanism by which perivascular adipose tissue-derived exosomes contribute to neuroinflammation and cognitive impairment in obesity and diabetes.

Cite This Study

Melvin R. Hayden (2022) studied this question.

synapsesocial.com/papers/6a8bef7960c8c47a9ee3f481 https://doi.org/10.3390/neuroglia3040008

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Implication

Suggests new therapeutic avenues for cognitive impairment in obesity and diabetes; leaves open clinical translation pending prospective studies.

Overview of Neuroglia Activation, Chronic Neuroinflammation, Remodeling, and Impaired Cognition Due to Perivascular Adipose Tissue-Derived Extracellular Vesicle Exosomes in Obesity and Diabetes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Overview of Neuroglia Activation, Chronic Neuroinflammation, Remodeling, and Impaired Cognition Due to Perivascular Adipose Tissue-Derived Extracellular Vesicle Exosomes in Obesity and Diabetes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider