January 7, 2014Hepatology

Treatment of Acute Portal Vein Thrombosis by Nontraditional Anticoagulation

View Full Paper

Ask AI

Bookmark

Why the study?

Does rivaroxaban improve acute portal vein thrombosis in a patient with compensated cirrhosis?

Population

A 50-year-old white man with extreme obesity, heart failure, hypertension, diabetes mellitus type 2, and…

Design

Case_report

Follow-up

6 months

Authors

MMMelissa MartínezCarilion Clinic ATAnand TandraEuropean Society for Blood and Marrow Transplantation RVRaj VuppalanchiIndiana University School of Medicine

Discussion

Member takes

Implication

May support rivaroxaban for acute PVT in compensated cirrhosis; hypothesis-generating, needs prospective validation.

Structured PICO

Does rivaroxaban improve acute portal vein thrombosis in a patient with compensated cirrhosis?

Population

A 50-year-old white man (n=1) with extreme obesity, heart failure, hypertension, diabetes mellitus type 2, and obstructive sleep apnea presenting with acute abdominal pain, diagnosed with nonalcoholic steatohepatitis related to Child-Pugh Class A cirrhosis (MELD 12) complicated by acute portal vein thrombosis (PVT) and mesenteric vein thrombosis (MVT).

Intervention

Unfractionated heparin given intravenously with subsequent transition to oral rivaroxaban 20 mg per day for 6 months.

Outcome

Complete resolution of the clot on CT scan at 6 monthssurrogate

Rivaroxaban successfully treated acute portal and mesenteric vein thrombosis in a patient with compensated cirrhosis without causing bleeding complications.

Cite This Study

Martínez et al. (2014) studied this question.

synapsesocial.com/papers/6a8bf085eada60f85de3d0c6 https://doi.org/10.1002/hep.26998

Topics

Anticoagulation in AF

View Full Paper

Ask AI

Bookmark

Treatment of Acute Portal Vein Thrombosis by Nontraditional Anticoagulation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Treatment of Acute Portal Vein Thrombosis by Nontraditional Anticoagulation

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider