Why the study?
Does felodipine reduce blood pressure in healthy male subjects?
Population
Healthy male subjects
Design
Other
Follow-up
at least 4 hours
Authors
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Supports PK/PD relationships in healthy volunteers; leaves open efficacy, dosing, and safety in hypertensive patients.
Does felodipine reduce blood pressure in healthy male subjects?
Felodipine acts predominantly as an arteriodilator, producing dose-dependent reductions in diastolic blood pressure that correlate closely with plasma concentrations.
Edgar et al. (1987) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: