A specific line of differentiation can be identified in the majority of tumors previously classified as malignant fibrous histiocytoma, suggesting the term should be reserved only for pleomorphic sarcomas without clear differentiation.
Supports reserving MFH for undifferentiated pleomorphic sarcomas; leaves open whether reclassification improves metastatic risk stratification.
(1997). Malignant fibrous histiocytoma—the commonest soft tissue sarcoma or a nonexistent entity? Acta Orthopaedica Scandinavica: Vol. 68, The Scandinavian—Australian Symposium on the Management of Bone and Soft Tissue Sarcomas, pp. 41-46.
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Måns Åkerman (1997) studied this question.
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