January 1, 2004Ultrastructural Pathology
The Rise and Fall of Malignant Fibrous Histiocytoma
Key result
Malignant fibrous histiocytomas are proposed to be reclassified as variants of pleomorphic fibrosarcoma, as recent studies show they are not derived from histiocytic facultative fibroblasts.
Design
Review
Authors
Discussion
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Member takes
Implication
May support updated sarcoma taxonomy; leaves open formal guideline adoption pending consensus validation.
PICO
P
Population
Malignant fibrous histiocytoma
The paper proposes a reclassification of malignant fibrous histiocytoma as variants of pleomorphic fibrosarcoma based on ultrastructural and immunohistochemical findings.
Cite This Study
Erlandson et al. (2004) conducted a review in Malignant fibrous histiocytoma. Malignant fibrous histiocytomas are proposed to be reclassified as variants of pleomorphic fibrosarcoma, as recent studies show they are not derived from histiocytic facultative fibroblasts.