Key result
Transcatheter implantation of a novel self-expanding pulmonary valve was successful in 3 of 5 male mini-pigs, with stable valve function and a mean gradient of 7 mmHg at 12 months follow-up.
Why the study?
Existing balloon-expandable pulmonary valves are intended for the main pulmonary trunk, limiting their utility in combined trunk and distal or proximal pulmonary artery dysfunction.
Does transcatheter implantation of a novel self-expanding pulmonary valve demonstrate safety and efficacy in a porcine model?
Does transcatheter implantation of a novel self-expanding pulmonary valve demonstrate safety and efficacy in a porcine model?
A novel self-expanding transcatheter pulmonary valve showed acceptable hemodynamics and no calcification at 12 months in a porcine model, though delivery system complications occurred in 2 of 5 animals.
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Rzaeva et al. (2023) studied Right ventricular outflow tract obstruction (animal model) (n=5). Transcatheter implantation of a self-expanding pulmonary valve was evaluated on Intra- and postoperative complications, safety, and efficacy of valve implantation. Transcatheter implantation of a novel self-expanding pulmonary valve was successful in 3 of 5 male mini-pigs, with stable valve function and a mean gradient of 7 mmHg at 12 months follow-up.
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