Population
Endothelial cells from rat brain microvessels and bovine aortic endothelial cells
Comparison
Endothelin-1 and related peptides vs Basic fibroblast growth factor
Design
Preclinical
Authors
Loading...
ET-1 receptors on rat brain endothelium may drive mitogenic signaling; leaves open translation to human cerebrovascular disease.
Endothelin-1 stimulates DNA synthesis and phosphatidylinositol hydrolysis in brain capillary endothelial cells, indicating they are a key target for this vasoactive peptide.
Vigne et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: