Key result
COPD in patients undergoing coronary artery bypass grafting increases the chances of a complicated in-hospital course by 2.1 times and the risk of long-term death by 1.8 times.
Why the study?
CAD and COPD frequently coexist to worsen quality of life and prognosis, prompting a review of postoperative outcomes for patients with COPD undergoing CABG.
What is the impact of comorbid COPD on postoperative outcomes and survival in patients undergoing CABG?
What is the impact of comorbid COPD on postoperative outcomes and survival in patients undergoing CABG?
Effect estimate: 2.1 times increased chance (in-hospital); 1.8 times increased risk (long-term)
Comorbid COPD significantly worsens both short-term complications and long-term survival in patients undergoing CABG, highlighting the need for risk stratification and tailored surgical approaches.
Associated risks support preoperative COPD evaluation in CABG; leaves open whether optimization improves outcomes.
Introduction. Cardiovascular disease is the leading cause of morbidity, disability and mortality in modern society. Coronary artery disease (CAD) and chronic obstructive pulmonary disease (COPD) are the most common comorbid pathology that worsens the quality of life and prospective prognosis of patients. Aim. The literature review is focused on postoperative outcomes of patients with COPD undergoing coronary artery bypass grafting surgery (CABG). Results. The review presents national and international data the prevalence of COPD in patients having CABG. The issues of risk stratification of comorbid patients in cardiac surgery are considered. It is shown that patients with CAD in combination with COPD are more at risk of various complications after CABG. COPD increases the chances of a complicated course of the in-hospital period by 2.1 times and risk of death in the long-term period after CAPG by 1.8 times. Patients with COPD are at a higher risk of developing postoperative pneumonia, respiratory failure, stroke, kidney failure, and wound infection of the sternum. Long-term 5-year and 10-year survival after CABG is lower in patients with COPD. The longterm adverse prognosis depends on the severity of the bronchial obstruction. Achievements in the field of cardiac surgery have had a significant impact on the results of surgical interventions in the comorbid course of CAD and COPD. Intensive pulmonary rehabilitation after surgery and effective drug therapy can improve the outcomes after CABG in patients with COPD. Hybrid coronary revascularization and minimally invasive coronary surgery appear to be viable alternatives to conventional CABG, offering a less invasive approach to coronary revascularization, which may be especially beneficial to high-risk patients with COPD.
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Atamas et al. (2021) conducted a review in Coronary artery disease and chronic obstructive pulmonary disease undergoing CABG. Chronic obstructive pulmonary disease (COPD) vs. No COPD was evaluated on Complicated course of the in-hospital period and risk of death in the long-term period (2.1 times increased chance (in-hospital); 1.8 times increased risk (long-term)). COPD in patients undergoing coronary artery bypass grafting increases the chances of a complicated in-hospital course by 2.1 times and the risk of long-term death by 1.8 times.
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