What question did this study set out to answer?

To elucidate the biosynthetic relationships and metabolic pathways generating phenolic compounds in mutant strains of Aspergillus terreus Thom.

January 1, 1964Biochemical JournalOpen Access

The biosynthesis of phenols. 5. The relationships of some phenolic metabolites of mutants of Aspergillus terreus Thom, I.M.I. 16043

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Authors

RCR. F. CurtisNorwich Research Park PHP. C. HarriesAberystwyth University CHC. H. HassallUniversity Hospital of the West Indies

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Implication

Spectroscopic analysis reveals distinct phenolic metabolite profiles in mutant strains of Aspergillus terreus, suggesting specific enzymatic steps in fungal phenol biosynthesis.

Key Points

To elucidate the biosynthetic relationships and metabolic pathways generating phenolic compounds in mutant strains of Aspergillus terreus Thom.
Measured ultraviolet-absorption spectra in ethanol solutions using Unicam SP. 500 or Optica CF 4 recording spectrophotometers.
Determined infrared-absorption spectra of samples prepared in potassium bromide disks with a Perkin-Elmer Infracord spectrometer, and recorded uncorrected melting points on a Kofler block.
Incorporated isotopically labelled precursor compounds obtained from The Radiochemical Centre to evaluate metabolic pathways.
Spectrophotometric profiles across ultraviolet and infrared spectra established distinct physical fingerprints for phenolic metabolites produced by fungal mutants.
Tracer incorporation and physical characterization demonstrated altered phenolic intermediary production across mutated Aspergillus terreus strains compared to parent controls.

Cite This Study

Curtis et al. (1964) studied this question.

synapsesocial.com/papers/6a8c69d351befdb68cc33cf6 https://doi.org/10.1042/bj0900043

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Implication

Spectroscopic analysis reveals distinct phenolic metabolite profiles in mutant strains of Aspergillus terreus, suggesting specific enzymatic steps in fungal phenol biosynthesis.

The biosynthesis of phenols. 5. The relationships of some phenolic metabolites of mutants of Aspergillus terreus Thom, I.M.I. 16043

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Implication

Key Points

Cite This Study

The biosynthesis of phenols. 5. The relationships of some phenolic metabolites of mutants of Aspergillus terreus Thom, I.M.I. 16043

Discussion

Member takes

Implication

Key Points

Cite This Study

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