Population
Intact dogs
Design
Preclinical
Authors
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May warrant caution against clinical extrapolation from canine models; leaves open need for human studies on vagal modulation in glycoside toxicity.
In a canine model, amyl nitrite and atropine can temporarily reverse ectopic ventricular beats induced by digitalis or strophanthin toxicity, alongside characteristic ECG changes.
Joanne Halsey (1917) studied this question.
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