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March 1, 2006The International Journal of Artificial Organs

Observation and Quantification of Cavitation on a Mechanical Heart Valve with an Electro-Hydraulic Total Artificial Heart

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Population

In vitro model using a 25-mm Medtronic Hall mechanical heart valve installed in the mitral position of an…

Design

Preclinical

Authors

HLH. LeeYTYuzo TaenakaNara Institute of Science and Technology

Discussion

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Implication

No PCO2 effect on cavitation in vitro; leaves open in vivo relevance for mechanical valve patients.

Structured PICO

P
Population
In vitro model using a 25-mm Medtronic Hall mechanical heart valve installed in the mitral position of an electro-hydraulic total artificial heart, using a 50% glycerin solution at 37 degrees C.
I
Intervention
Controlled partial pressure of CO2 (PCO2) at heart rates of 60, 70, and 100 bpm.
O
Outcome
Cavitation intensity quantified using a high-speed camera.surrogate

In an in vitro model of a mechanical heart valve, varying the partial pressure of CO2 did not significantly affect cavitation intensity.

Cite This Study

Lee et al. (2006) studied this question.

synapsesocial.com/papers/6a8c84d09318834dded934fehttps://doi.org/10.1177/039139880602900308
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Observation and Quantification of Gas Bubble Formation on a Mechanical Heart Valve2000 · 41 citations
  2. 2In Vivo Observation of Cavitation on Prosthetic Heart Valves1996 · 42 citations
  3. 3Origin and Appearance of HITS Induced by Prosthetic Heart Valves: An in vitro Study2000 · 18 citations
  4. 4Influence of Oxygen Ventilation on Doppler Microemboli Signals in Patients With Artificial Heart Valves1997 · 44 citations
  5. 5Mechanism for Cavitation in the Mechanical Heart Valve With an Artificial Heart: Nuclei and Viscosity Dependence2005 · 16 citations