Why the study?
What are the cardiovascular mechanisms underlying functional aerobic impairment in patients with coronary heart disease?
Population
53 men, comprising 42 men with coronary heart disease and 11 slightly older healthy men.
Comparison
Exercise testing vs Healthy men, and comparison between coronary…
Design
Cross-sectional
Authors
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Identifies central limits to exercise capacity in angina; leaves open whether these mechanisms should guide testing or interventions.
What are the cardiovascular mechanisms underlying functional aerobic impairment in patients with coronary heart disease?
Restricted stroke volume and reduced heart rate are the primary cardiovascular mechanisms responsible for functional aerobic impairment in patients with myocardial ischemia.
Bruce et al. (1974) studied this question.
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