Why the study?
Does cardiac resynchronization therapy reduce peripheral markers of immune activation in patients with heart failure?
Population
8 patients with heart failure scheduled for cardiac resynchronization therapy (CRT)
Comparison
Cardiac resynchronization therapy (CRT) vs Baseline (before CRT treatment)
Design
Case_series
Follow-up
6 months
Authors
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Supports potential immunomodulatory effects of CRT in HF; hypothesis-generating and requires prospective confirmation.
Does cardiac resynchronization therapy reduce peripheral markers of immune activation in patients with heart failure?
Cardiac resynchronization therapy may reduce peripheral markers of immune activation in patients with heart failure, which correlates with improvements in BNP.
Lappegård et al. (2006) studied this question.
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