Why the study?
Does prophylactic heparin treatment reduce enhanced thrombin generation in thrombosis-prone pregnant women?
Population
69 pregnant women, comprising 43 thrombosis-prone women and 26 healthy controls
Comparison
Subcutaneous heparin treatment during pregnancy… vs Healthy pregnant women (control group)
Design
Cohort
Follow-up
throughout pregnancy
Authors
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Heparin may reduce thrombin markers in high-risk pregnancies; hypothesis-generating and should not change practice without trials.
Does prophylactic heparin treatment reduce enhanced thrombin generation in thrombosis-prone pregnant women?
Prophylactic heparin in thrombosis-prone pregnant women partially normalizes elevated markers of coagulation activation.
Bremme et al. (1993) studied this question.
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