Why the study?
Does the withdrawal of long-term antihypertensive treatment lead to a sustained rise in blood pressure in patients with mild hypertension?
Population
2,765 adults aged 35-64 with mild hypertension who had been on long-term antihypertensive treatment with…
Comparison
Withdrawal of long-term antihypertensive… vs Continuation of long-term antihypertensive…
Design
RCT, randomly allocated
Follow-up
two years
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Indefinite antihypertensive therapy warranted in mild hypertension; challenges assumption of permanent blood pressure reset after long-term treatment.
Does the withdrawal of long-term antihypertensive treatment lead to a sustained rise in blood pressure in patients with mild hypertension?
Withdrawal of long-term antihypertensive therapy in mild hypertension results in a rapid loss of blood pressure control within one year, demonstrating that treatment does not permanently reset blood pressure control mechanisms.
A 1986 study studied this question.
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