Why the study?
Cardiac damage significantly affects prognosis in aortic stenosis, but its impact on long-term survival across moderate and severe aortic stenosis required investigation.
Does aortic valve replacement reduce mortality compared with conservative management in patients with moderate and severe aortic stenosis according to the extent of cardiac damage?
Does aortic valve replacement reduce mortality compared with conservative management in patients with moderate and severe aortic stenosis according to the extent of cardiac damage?
Aortic valve replacement is associated with reduced long-term mortality in patients with moderate aortic stenosis if they have advanced cardiac damage.
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Advanced CD staging may refine AS risk stratification; leaves open whether it guides intervention timing in moderate disease.
Angellotti et al. (2025) studied this question.
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