Why the study?
Does a negative aneurysm screen eliminate the long-term risk of aneurysmal subarachnoid hemorrhage in persons with one first-degree relative with aSAH?
Population
601 asymptomatic first-degree relatives of patients with aneurysmal subarachnoid hemorrhage who had a…
Comparison
Observational follow-up after a negative MRA… vs General population
Design
Cohort
Follow-up
mean 14.9 years (range 2-16 years)
Authors
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Negative screening leaves residual aSAH risk in familial cases; leaves open need for surveillance trials.
Does a negative aneurysm screen eliminate the long-term risk of aneurysmal subarachnoid hemorrhage in persons with one first-degree relative with aSAH?
In persons with one first-degree relative with aSAH, a negative aneurysm screen does not eliminate the long-term risk of aSAH, which remains comparable to or slightly higher than that of the general population over 15 years.
Rasing et al. (2015) studied this question.
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