October 1, 1992AJP Heart and Circulatory Physiology

Spinal stimulation to locate preganglionic neurons controlling the kidney, spleen, or intestine

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Population

Urethan-anesthetized rats

Design

Preclinical

Authors

RTRoy TaylorWestern University LWLynne C. WeaverWestern University

Discussion

Member takes

Implication

Supports differential spinal sympathetic control of kidney versus spleen/intestine in animals; hypothesis-generating for selective neuromodulation in humans.

Structured PICO

Population

Urethan-anesthetized rats

Intervention

Microinjection of D,L-homocysteic acid (3 nl, 0.17 M) into the lateral gray matter of the third thoracic (T3) to the fourth lumbar (L4) spinal segments

Outcome

Discharge of renal, splenic, and mesenteric postganglionic nervessurrogate

Sympathetic output to the kidney, spleen, and intestine can be differentiated at the level of the spinal cord, despite widely overlapping spinal cord segments controlling these organs.

Cite This Study

Taylor et al. (1992) studied this question.

synapsesocial.com/papers/6a8cfdea029556da77eaa83e https://doi.org/10.1152/ajpheart.1992.263.4.h1026

View Full Paper

Ask AI

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Implication

Supports differential spinal sympathetic control of kidney versus spleen/intestine in animals; hypothesis-generating for selective neuromodulation in humans.

Spinal stimulation to locate preganglionic neurons controlling the kidney, spleen, or intestine

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Spinal stimulation to locate preganglionic neurons controlling the kidney, spleen, or intestine

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider