Why the study?
Does intrarenal infusion of angiotensin IV or LVV-hemorphin-7 alter renal blood flow in anesthetized rats?
Does intrarenal infusion of angiotensin IV or LVV-hemorphin-7 alter renal blood flow in anesthetized rats?
In anesthetized rats, angiotensin IV produces renal vasoconstriction mediated by AT1 receptors, providing evidence against a vasodilatory role of putative AT4 receptors in the rat kidney.
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Evidence against AT4-mediated renal vasodilation in rats; challenges prior hypotheses while leaving human translation open.
Fitzgerald et al. (1999) studied this question.
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