Population
Intact-chest cats under conditions of controlled blood flow and constant left atrial pressure
Design
Preclinical
Authors
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Should not alter clinical practice; leaves open translation of feline pulmonary angiotensin effects to human disease.
In a feline model, angiotensin I, II, and III exhibit similar pulmonary pressor activities mediated by AT1 receptors, with ACE inhibition selectively attenuating ANG I responses and enhancing bradykinin-induced vasodilation.
Cheng et al. (1994) studied this question.
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