Determinants of exercise-induced pulmonary hypertension in patients with normal left ventricular ejection fraction
Why the study?
What are the clinical and echocardiographic determinants of exercise-induced pulmonary hypertension in patients with normal left ventricular ejection fraction?
Population
396 subjects (160 male, mean age 55) with normal left ventricular ejection fraction referred for exercise…
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
May inform noninvasive risk stratification for exercise PH in normal LVEF; leaves open prospective outcome validation.
Structured PICO
What are the clinical and echocardiographic determinants of exercise-induced pulmonary hypertension in patients with normal left ventricular ejection fraction?
P
Population
396 subjects (160 male, mean age 55 (SD 13)) with normal left ventricular ejection fraction referred for exercise echocardiography
I
Intervention
Graded, symptom-limited, supine bicycle exercise with two-dimensional and Doppler echocardiography
O
Outcome
Determinants of exercise-induced pulmonary hypertension (defined as pulmonary artery systolic pressure >50 mm Hg at 50 W of exercise)surrogate
Exercise-induced pulmonary hypertension is common in patients with normal LVEF and is strongly predicted by resting TR velocity, E/E' ratio, age, and gender.
Cite This Study
Ha et al. (2008) studied this question.