Why the study?
Does circulating angiotensin II regulate glomerular filtration rate during reduced renal artery pressure in sodium-depleted dogs?
Does circulating angiotensin II regulate glomerular filtration rate during reduced renal artery pressure in sodium-depleted dogs?
Circulating angiotensin II plays an important role in regulating efferent arteriolar resistance and glomerular filtration rate during reductions in renal artery pressure.
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Suggests ANG II supports GFR via efferent tone in experimental hypoperfusion; leaves open translation to human cardiorenal states.
Hall et al. (1981) studied this question.
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