Key result
The renin-angiotensin system regulates glomerular filtration by acting on arteriolar resistance, glomerular capillary surface area, and the ultrafiltration coefficient.
Design
Review
Authors
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May inform RAS inhibitor use in CKD; leaves open targeted trials on ultrafiltration effects.
This review summarizes the physiological mechanisms by which the intrarenal renin-angiotensin system regulates glomerular filtration rate and renal plasma flow.
Sraer et al. (1989) reported a review. Renin-Angiotensin System was evaluated. The renin-angiotensin system regulates glomerular filtration by acting on arteriolar resistance, glomerular capillary surface area, and the ultrafiltration coefficient.