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March 1, 1995AJP Heart and Circulatory Physiology

Validation of 1- and 2-mm transit-time ultrasound flow probes on mesenteric artery and aorta of rats

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Population

Rats (mesenteric artery and aorta)

Comparison

1- and 2-mm transit-time ultrasound perivascular… vs True flow measured by timed-volume measurements…

Design

Preclinical

Authors

MDMark S. D'AlmeidaUniversity of ManitobaCGChristophe GaudinCIEPDLDidier LebrecHôpital Beaujon

Discussion

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Implication

Accurate flow measurement possible with 1-mm probes in rats; extends tool validation but should not yet inform clinical practice.

Structured PICO

P
Population
Rats (mesenteric artery and aorta)
I
Intervention
1- and 2-mm transit-time ultrasound perivascular flow probes
C
Comparator
True flow measured by timed-volume measurements with a blood/saline pump-perfused circuit
O
Outcome
Accuracy and calibration of flow measurement (relationship between measured flow and true flow)surrogate

Transit-time ultrasound flow probes (1-mm and 2-mm) provide linear measurements of blood flow in rat arteries, with the 1-mm probe being highly accurate and the 2-mm probe having a specific window of accuracy.

Cite This Study

D'Almeida et al. (1995) studied this question.

synapsesocial.com/papers/6a8d1cb60bd5a3045f314c6bhttps://doi.org/10.1152/ajpheart.1995.268.3.h1368
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of a transit-time system for the chronic measurement of blood flow in conscious sheep1995 · 64 citations
  2. 2Validation of transit-time flowmetry for chronic measurements of regional blood flow in resting and exercising rats1997 · 16 citations
  3. 3Volume blood flow measurements with a transit time flowmeter: an in vivo and in vitro variability and validation study1993 · 134 citations
  4. 4Validation of Transonic Small Animal Flowmeter for Measurement of Cardiac Output and Regional Blood Flow in the Rat1996 · 44 citations
  5. 5Comparison of Transit-Time and Doppler Ultrasound Methods for Measurement of Flow in Aortocoronary Bypass Grafts during Cardiac Surgery1994 · 31 citations