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September 1, 1993Clinical Physiology

Volume blood flow measurements with a transit time flowmeter: an in vivo and in vitro variability and validation study

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Population

Sheep carotid arteries for in vivo experiments and a pre-calibrated rotational pump for in vitro experiments.

Comparison

Volume blood flow measurement using Transonic… vs Exsanguination measurements and pre-calibrated…

Design

Preclinical

Authors

ALAnna LundellUppsala UniversityDBDavid BergqvistVascular / Pulmonary VascularEMErney MattssonNorwegian University of Science and Technology

Discussion

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Implication

Supports flowmeter validation in animal models; leaves open clinical translation pending human studies.

Structured PICO

P
Population
Sheep carotid arteries (n=16) for in vivo experiments and a pre-calibrated rotational pump for in vitro experiments.
I
Intervention
Volume blood flow measurement using Transonic TC101 transit time flowmeter with 4 mm and 6 mm probes.
C
Comparator
Exsanguination measurements (in vivo, n=32) and pre-calibrated rotational pump (in vitro).
O
Outcome
Error of measurement and variability of volume flow.surrogate

The Transonic TC101 transit time flowmeter demonstrates small variability and error of measurement for volume blood flow in both in vivo and in vitro settings.

Cite This Study

Lundell et al. (1993) studied this question.

synapsesocial.com/papers/6a8718566fbb37794f7cb76chttps://doi.org/10.1111/j.1475-097x.1993.tb00470.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Validation of 1- and 2-mm transit-time ultrasound flow probes on mesenteric artery and aorta of rats1995 · 43 citations
  2. 2Evaluation of a transit-time system for the chronic measurement of blood flow in conscious sheep1995 · 65 citations
  3. 3<i>In Vivo</i> Validation of Magnetic Resonance Blood Volume Flow Measurements with Limited Spatial Resolution in Small Vessels1995 · 154 citations
  4. 4Validation of transit-time flowmetry for chronic measurements of regional blood flow in resting and exercising rats1997 · 16 citations
  5. 5Comparison of Transit-Time and Doppler Ultrasound Methods for Measurement of Flow in Aortocoronary Bypass Grafts during Cardiac Surgery1994 · 31 citations