January 4, 2010Circulation
Endogenous Erythropoietin and Outcome in Heart Failure
Why the study?
Do higher endogenous erythropoietin levels predict increased mortality in patients hospitalized for heart failure?
Population
605 patients hospitalized for heart failure, mean age 71+/-11 years, 62% male, mean left ventricular…
Comparison
Higher endogenous erythropoietin levels vs Lower endogenous erythropoietin levels
Design
Cohort
Follow-up
18 months
Authors
Discussion
Loading...
Member takes
Implication
May aid mortality risk stratification in hospitalized HF; leaves open whether erythropoietin is a modifiable target.
Structured PICO
Do higher endogenous erythropoietin levels predict increased mortality in patients hospitalized for heart failure?
P
Population
605 patients hospitalized for heart failure, mean age 71+/-11 years, 62% male, mean left ventricular ejection fraction 0.33+/-0.14.
I
Intervention
Higher endogenous erythropoietin levels (measured at discharge and after 6 months)
C
Comparator
Lower endogenous erythropoietin levels
O
Outcome
Mortality at 18 monthshard clinical
Higher and persistently elevated endogenous erythropoietin levels are independent predictors of increased mortality in patients with heart failure.
Cite This Study
Belonje et al. (2010) studied this question.