Why the study?
Does lower body subatmospheric pressure (LBNP) alter blood and plasma mass density and hematocrit in humans?
Population
12 human subjects in the supine position
Comparison
20-40 min of lower body subatmospheric pressure… vs Baseline (before LBNP) and recovery (after LBNP)
Design
Other
Follow-up
20-40 min of LBNP plus recovery period
Authors
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LBNP-induced fluid shifts are quantifiable by mass densitometry; hypothesis-generating for orthostatic research and should not yet change clinical volume assessment.
Does lower body subatmospheric pressure (LBNP) alter blood and plasma mass density and hematocrit in humans?
Sudden unloading of central pressure receptors with LBNP causes biphasic microvascular fluid shifts, which can be quantified with high-precision mass densitometry.
Hinghofer‐Szalkay et al. (1992) studied this question.
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