Why the study?
Does lower body negative pressure increase coagulation markers in healthy male volunteers?
Population
10 healthy male volunteers
Design
Other
Follow-up
10 min
Authors
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May signal thrombin activation during central hypovolemia in healthy volunteers; hypothesis-generating and requires confirmation before clinical relevance.
Does lower body negative pressure increase coagulation markers in healthy male volunteers?
A modest decrease in central blood volume induced by lower body negative pressure activates thrombin generation in healthy humans.
Zaar et al. (2009) studied this question.
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