Why the study?
Does lower body negative pressure (LBNP) model the white blood cell response to experimental blood loss in men?
Population
12 men
Comparison
Simulated hypovolaemia using 45 mmHg of lower… vs Real hypovolaemia induced via 1000 ml of…
Design
Other, randomized order
Authors
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LBNP may model early WBC mobilization during hypovolemia; hypothesis-generating and requires clinical validation.
Does lower body negative pressure (LBNP) model the white blood cell response to experimental blood loss in men?
Lower body negative pressure appears to be a valid surrogate model for studying the early white blood cell mobilization response to central hypovolemia and blood loss in humans.
Helmond et al. (2016) studied this question.
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