November 10, 2003Catheterization and Cardiovascular Interventions

The porcine coronary model of in‐stent restenosis: Current status in the era of drug‐eluting stents

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Population

Porcine coronary model of in-stent restenosis

Design

Review

Authors

HLHarry C. LoweRoyal Prince Alfred Hospital RSRobert S. SchwartzGeneral Cardiology BNBriain D. Mac NeillHarvard University

Discussion

Member takes

Implication

Supports preclinical DES testing in porcine models; extends research tools but leaves clinical translation open.

Structured PICO

Population

Porcine coronary model of in-stent restenosis

Intervention

Drug-eluting stents (including sirolimus-eluting stents)

Outcome

Histologic response, mechanisms of action, toxicity, and biocompatibility

This review provides a comprehensive overview of the porcine coronary model of in-stent restenosis, which is crucial for evaluating the efficacy and safety of novel drug-eluting stents before human trials.

Cite This Study

Lowe et al. (2003) studied this question.

synapsesocial.com/papers/6a8d3bc837479a8d604ac4ea https://doi.org/10.1002/ccd.10705

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The porcine coronary model of in‐stent restenosis: Current status in the era of drug‐eluting stents

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The porcine coronary model of in‐stent restenosis: Current status in the era of drug‐eluting stents

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider