Population
Human prothrombin and its fragments (in vitro biochemical study)
Comparison
Various prothrombin fragments vs Other plasma proteins and NH2-terminal large…
Design
Preclinical
Authors
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No immediate clinical implications for coagulopathy management; leaves open targeted disruption of staphylocoagulase-prothrombin binding for future studies.
The study identifies the COOH-terminal region of the alpha-thrombin B chain as the specific binding site for staphylocoagulase on human prothrombin.
Kawabata et al. (1985) studied this question.
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