Key result
Patients with both OSA and hypertension demonstrated significantly lower adiponectin levels, increased inflammatory markers, and altered lipid profiles compared to controls or those with either condition alone.
Why the study?
Are adiponectin levels, inflammatory markers, and lipid profiles altered in patients with obstructive sleep apnea and hypertension compared to those with either condition alone or healthy controls?
Case-Control (n=88)
Are adiponectin levels, inflammatory markers, and lipid profiles altered in patients with obstructive sleep apnea and hypertension compared to those with either condition alone or healthy controls?
The combination of obstructive sleep apnea and hypertension is associated with a more pronounced pro-inflammatory and atherogenic biomarker profile, including lower adiponectin levels, than either condition alone.
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Suggests a synergistic pro-inflammatory and atherogenic risk profile in combined OSA and hypertension; leaves.
Abdel-Fadeil et al. (2017) conducted a case-control in Obstructive sleep apnea and hypertension (n=88). Obstructive sleep apnea and hypertension vs. Healthy controls and patients with hypertension alone was evaluated on Morning and evening serum adiponectin, inflammatory markers (TNF-α, IL-6), and lipid profiles. Patients with both OSA and hypertension demonstrated significantly lower adiponectin levels, increased inflammatory markers, and altered lipid profiles compared to controls or those with either condition alone.
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