Key result
A 12-month physician-supervised exercise training program for patients with heart failure was feasible and safe, yielding a subtle increase in peak VO2% predicted from 66.5% to 67% (p for trend = 0.03).
Why the study?
Exercise training in heart failure is recommended but not routinely offered due to logistic and safety reasons; this study aimed to evaluate the feasibility and safety of establishing a dedicated HF training group in Germany.
Does a supervised heart failure exercise program improve peakVO2 and other surrogate markers in patients with symptomatic heart failure and LVEF ≤ 45%?
Population
12 patients with symptomatic HF (NYHA class II/III) and LVEF <= 45%
Comparison
Weekly physician-supervised exercise training with a wrist-worn pedometer
Design
Single-arm feasibility study with blinded echocardiography reading
Follow-up
1 year
Authors
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Supports the initial feasibility of dedicated exercise groups for symptomatic HF; leaves open whether broader implementation improves.
Cohort (n=12)
Open-label
No
Does a supervised heart failure exercise program improve peakVO2 and other surrogate markers in patients with symptomatic heart failure and LVEF ≤ 45%?
p-value: p=0.03
A supervised, dedicated exercise training group for patients with heart failure is feasible, safe, and associated with improvements in quality of life, LVEF, and NT-proBNP over 12 months.
Güder et al. (2021) conducted a cohort in Heart failure (n=12). Physician-supervised exercise training was evaluated on 12-month change in peak VO2 at cardiopulmonary exercise testing (p=0.03). A 12-month physician-supervised exercise training program for patients with heart failure was feasible and safe, yielding a subtle increase in peak VO2% predicted from 66.5% to 67% (p for trend = 0.03).
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