Key result
During contraction of vertebrate smooth muscle cells, myofilaments progressively change their orientation from nearly parallel to the cell's main axis to an undulating or helical pattern.
Population
Stomach muscle cells of Bufo marinus
Comparison
Muscle contraction vs Relaxed muscle cells
Design
Preclinical
Authors
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May refine models of smooth muscle mechanics; hypothesis-generating and requires human validation before clinical relevance.
Demonstrates that myofilaments in vertebrate smooth muscle change orientation from parallel to oblique or helical during contraction.
Fisher et al. (1977) studied Smooth muscle contraction. Muscle contraction vs. Relaxed cells was evaluated on Orientation of filaments within smooth muscle cells. During contraction of vertebrate smooth muscle cells, myofilaments progressively change their orientation from nearly parallel to the cell's main axis to an undulating or helical pattern.
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