Key result
Obesity in adolescents is associated with significantly worse endothelial function compared to lean controls, as measured by a lower RH-PAT score (1.70 vs. 1.98, p=0.02).
Population
51 adolescents, predominantly Hispanic and African American, recruited from clinics in New York City…
Design
Cross-sectional
Authors
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May signal early atherosclerotic risk in obese adolescents; leaves open whether endothelial dysfunction predicts clinical events.
Cross-Sectional (n=51)
No
Absolute Event Rate: 1.7% vs 1.98%
p-value: p=0.02
Obesity and impaired glucose regulation in adolescents are associated with impaired endothelial function, insulin resistance, and inflammation, suggesting early preclinical atherosclerotic changes.
Agarwal et al. (2013) conducted a cross-sectional in Obesity and Endothelial Dysfunction (n=51). Obesity vs. Lean controls was evaluated on Endothelial function measured by RH-PAT score (p=0.02). Obesity in adolescents is associated with significantly worse endothelial function compared to lean controls, as measured by a lower RH-PAT score (1.70 vs. 1.98, p=0.02).
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