What question did this study set out to answer?

To evaluate the tyrosinase inhibitory potential of plant bioactives extracted with natural deep eutectic solvents and determine if laccase-mediated polymerization enhances their bioactivity.

May 14, 2025CatalystsOpen Access

Laccase-Catalyzed Polymerized Natural Bioactives for Enhanced Mushroom Tyrosinase Inhibition

View Full Paper

Ask AI

Bookmark

Authors

DRDiana RochaUnited Nations University JSJoana SantosUniversity of Minho JNJennifer NoroCentre Universitaire de Labé

Discussion

Member takes

Implication

In vitro study demonstrates enhanced tyrosinase inhibition by laccase-polymerized natural extracts, highlighting a sustainable green approach for hyperpigmentation treatment.

Key Points

To evaluate the tyrosinase inhibitory potential of plant bioactives extracted with natural deep eutectic solvents and determine if laccase-mediated polymerization enhances their bioactivity.
Extracted bioactive compounds from acorn, cocoa, cork, and eucalyptus using hydroethanolic mixtures and natural deep eutectic solvents (NADES).
Subjected the extracts to laccase-mediated polymerization and evaluated their inhibitory activity against mushroom tyrosinase relative to standard kojic acid.
NADES significantly improved extraction yields and preserved bioactive compounds compared to hydroethanolic solvents, with cocoa extracts exhibiting the highest baseline tyrosinase inhibition.
Laccase-catalyzed polymerization further amplified tyrosinase inhibitory activity across extracts, achieving the most pronounced enhancement in NADES-derived preparations.

Cite This Study

Rocha et al. (2025) studied this question.

synapsesocial.com/papers/6a8df8d27185663cec9aae85 https://doi.org/10.3390/catal15050481

View Full Paper

Ask AI

Bookmark

Implication

In vitro study demonstrates enhanced tyrosinase inhibition by laccase-polymerized natural extracts, highlighting a sustainable green approach for hyperpigmentation treatment.

Laccase-Catalyzed Polymerized Natural Bioactives for Enhanced Mushroom Tyrosinase Inhibition

Discussion

Member takes

Implication

Key Points

Cite This Study

Laccase-Catalyzed Polymerized Natural Bioactives for Enhanced Mushroom Tyrosinase Inhibition

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider