Population
PK15 and Cos-7 cells
Comparison
Porcine circovirus type 2 infection and ORF3… vs ORF3-deficient PCV2 infection or absence of ORF3…
Design
Preclinical
Authors
Loading...
May guide PCV2 intervention strategies in swine; leaves open whether ORF3 targeting alters disease outcomes in vivo.
The novel ORF3 protein of PCV2 plays a major role in virus-induced apoptosis via the caspase-8 and caspase-3 pathways.
Liu et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: