Adipose inflammation is associated with increased systemic inflammation, reduced insulin sensitivity, and reduced skeletal muscle mitochondrial respiration in obesity.
Observational
Adipose tissue inflammation is linked to systemic metabolic derangements in obesity, including insulin resistance and reduced mitochondrial respiration.
Adipose inflammation is proposed to be at the nexus of the systemic inflammation and metabolic derangements associated with obesity. The present study provides evidence to support adipose inflammation as a central feature of the pathophysiology of obesity. Adipose inflammation is associated with systemic and peripheral metabolic derangements, including increased systemic inflammation, reduced insulin sensitivity, and reduced skeletal muscle mitochondrial respiration.
Kunz et al. (Mon,) conducted a observational in obesity. Adipose inflammation was evaluated on systemic inflammation, insulin sensitivity, and skeletal muscle mitochondrial respiration. Adipose inflammation is associated with increased systemic inflammation, reduced insulin sensitivity, and reduced skeletal muscle mitochondrial respiration in obesity.