Key result
Desflurane showed no significant difference in time to following commands compared to propofol (MD 0.7 min; 95% CI -0.2 to 1.7), but was 4.4 min faster than isoflurane.
Why the study?
Does desflurane reduce time to following commands and time to discharge compared to isoflurane or propofol in surgical patients?
Population
545 patients undergoing surgery with planned extubation at the end of surgery and general anesthesia induced…
Comparison
Desflurane vs Isoflurane or propofol
Design
Meta-analysis, randomly assigned to groups
Authors
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Clinicians may select anesthetics based on factors other than recovery speed; meta-analysis confirms only minor differences among agents.
Meta-Analysis (n=545)
Randomized
Does desflurane reduce time to following commands and time to discharge compared to isoflurane or propofol in surgical patients?
Mean Difference: 0.7 (95% CI -0.2–1.7)
There are only minor clinically important differences between desflurane and isoflurane or propofol regarding recovery times.
Dexter et al. (1995) conducted a meta-analysis in General anesthesia for surgery (n=545). Desflurane vs. Isoflurane or propofol was evaluated on Time to following commands (desflurane vs propofol) (MD 0.7, 95% CI -0.2 to 1.7). Desflurane showed no significant difference in time to following commands compared to propofol (MD 0.7 min; 95% CI -0.2 to 1.7), but was 4.4 min faster than isoflurane.
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