Key result
Intracerebroventricular infusion of angiotensin II in rats elicits an early phase of sodium ingestion followed by urinary sodium excretion exceeding intake, leading to hyponatremia and hypovolemia.
Authors
Loading...
Does not support changes in hyponatremia management; leaves open central angiotensin II pathways as a research target in volume regulation.
Fluharty et al. (1983) studied this question. Intracerebroventricular infusion of angiotensin II was evaluated on Sodium appetite and urinary sodium excretion. Intracerebroventricular infusion of angiotensin II in rats elicits an early phase of sodium ingestion followed by urinary sodium excretion exceeding intake, leading to hyponatremia and hypovolemia.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: