Why the study?
Does Antithrombin III supplementation prevent organ failure in sepsis and ischemia/reperfusion injury?
Does Antithrombin III supplementation prevent organ failure in sepsis and ischemia/reperfusion injury?
Antithrombin III exerts anti-inflammatory effects independent of its anticoagulant properties, suggesting potential therapeutic utility in preventing organ failure in sepsis and ischemia/reperfusion injury.
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Supports AT III investigation for sepsis organ injury; hypothesis-generating from animal data and should not change practice.
Okajima et al. (1998) studied this question.
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