Population
Actin and tropomyosin proteins
Design
Preclinical
Authors
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No clinical implications yet; leaves open their role in cardiac thin-filament regulation in vivo.
Mutagenesis studies provide the first experimental support for atomic models of the actin-tropomyosin interface, highlighting the importance of specific basic and acidic residues.
Barua et al. (2013) studied this question.
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