Atropine and a Hypertensive Crisis

Letters and Corrections1 November 1984Atropine and a Hypertensive CrisisSHOJI SESOKO, M.D., NAOMICHI MIYAZAKI, M.D., YOSHIO KATO, M.D., OSAMU TOCHIKUBO, M.D., YOSHIHIRO KANEKO, M.D.SHOJI SESOKO, M.D., NAOMICHI MIYAZAKI, M.D., YOSHIO KATO, M.D., OSAMU TOCHIKUBO, M.D., YOSHIHIRO KANEKO, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-101-5-720_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The relation between parasympathetic nerve activity and hypertension is still not clear, although the mechanisms whereby the sympathetic nervous system affects blood pressure have been clarified in recent studies. To investigate the parasympathetic nerve mechanisms contributing to hypertension, we have been carrying out studies with atropine injections (1, 2) in hypertensive patients. We report a case with evidence that atropine injection induced a hypertensive crisis in a patient with hypertension.A 28-year-old man was found to have hypertension (blood pressure 188/90 mm Hg) and proteinuria, but not renal dysfunction (serum creatinine level, 1.2 mg/dL) in May 1982....References1. JULIUSPASCUALLONDON SAR. Role of parasympathetic inhibition in the hyperkinetic type of borderline hypertension. Circulation. 1971;44:413-8. CrossrefMedlineGoogle Scholar2. PICKERINGGRIBBONPETERSENCUNNINGHAMSLEIGHT TBEJP. Effects of autonomic blockade on the baroreflex in man at rest and during exercise. Circ Res. 1972;30:177-85. CrossrefMedlineGoogle Scholar3. MAN IN'T VELDWENTINGBOOMSMAVERHOEVENSCHALEKAMP AGFRM. Sympathetic and parasympathetic components of reflex cardiostimulation during vasodilator treatment of hypertension. Br J Clin Pharmacol. 1980;9:547-51. CrossrefMedlineGoogle Scholar4. TRIMARCOVOLPERICCIARDELLI BMB. Baroreflex responsiveness in borderline hypertensives: a study with neostigmine. Cardiovasc Res. 1981;15:436-42. CrossrefMedlineGoogle Scholar5. PFEIFERWEINBERGCOOKBESTREENANHALTER MCDJAJ. Differential changes of autonomic nervous system function with age in man. Am J Med. 1983;75:249-58. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Yokohama City University, School of Medicine Yokohama 232 Japan PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPathophysiology, clinical aspects, and treatment of hypertensive crisesLetters to the Editor and Informed ConsentDAVID NAYLOR, M.D., D. Phil.Pseudopheochromocytoma. 1 November 1984Volume 101, Issue 5Page: 720-720KeywordsAtropineBlood pressureCreatinineHypertensionNervesProteinuriaSympathetic nervous system ePublished: 1 December 2008 Issue Published: 1 November 1984 PDF downloadLoading ...